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Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress
The activation of hepatic stellate cells (HSCs) plays a vital role in the progression of liver fibrosis, and the induction of HSCs apoptosis may attenuate or reverse fibrogenesis. The therapeutic effects of etoposide(VP-16), a widely used anticancer agent, on HSCs apoptosis and liver fibrosis resolu...
Autores principales: | Wang, Chen, Zhang, Feng, Cao, Yu, Zhang, Mingming, Wang, Aixiu, Xu, Mingcui, Su, Min, Zhang, Ming, Zhuge, Yuzheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041150/ https://www.ncbi.nlm.nih.gov/pubmed/27680712 http://dx.doi.org/10.1038/srep34330 |
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