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Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress

The activation of hepatic stellate cells (HSCs) plays a vital role in the progression of liver fibrosis, and the induction of HSCs apoptosis may attenuate or reverse fibrogenesis. The therapeutic effects of etoposide(VP-16), a widely used anticancer agent, on HSCs apoptosis and liver fibrosis resolu...

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Detalles Bibliográficos
Autores principales:	Wang, Chen, Zhang, Feng, Cao, Yu, Zhang, Mingming, Wang, Aixiu, Xu, Mingcui, Su, Min, Zhang, Ming, Zhuge, Yuzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041150/ https://www.ncbi.nlm.nih.gov/pubmed/27680712 http://dx.doi.org/10.1038/srep34330

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