Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro

BACKGROUND: There is some evidence that ATP binding cassette (ABC) transporters play a role in resistance to anthelmintics, particularly against macrocyclic lactones. Some anthelmintics, including ivermectin (IVM), have been shown to induce transcription of multiple ABC transporters in nematodes; ho...

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Detalles Bibliográficos
Autores principales: Raza, Ali, Bagnall, Neil H., Jabbar, Abdul, Kopp, Steven R., Kotze, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041279/
https://www.ncbi.nlm.nih.gov/pubmed/27682865
http://dx.doi.org/10.1186/s13071-016-1806-9

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