Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice

BACKGROUND: Neuroinflammation is a proposed mechanism by which Alzheimer’s disease (AD) pathology potentiates neuronal death and cognitive decline. Consumption of omega-3 polyunsaturated fatty acids (PUFA) is associated with a decreased risk of AD in human observational studies and exerts protective...

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Detalles Bibliográficos
Autores principales: Hopperton, Kathryn E., Trépanier, Marc-Olivier, Giuliano, Vanessa, Bazinet, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041295/
https://www.ncbi.nlm.nih.gov/pubmed/27688126
http://dx.doi.org/10.1186/s12974-016-0721-5

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