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Cellular effects induced by 17-β-estradiol to reduce the survival of renal cell carcinoma cells

BACKGROUND: Renal cell carcinoma (RCC) is an adult malignancy with 2:1 men-to-women ratio, which implies the possible role of sex hormones in RCC carcinogenesis. One of the predominant sex hormones in women before menopause, 17-β-estradiol (or E2), may regulate RCC growth by cellular mechanisms that...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Tang, Ku, Wei-Chi, Huang, Chi-Jung, Wang, Yen-Chieh, Lin, Chih-Ming, Chen, Shao-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041337/
https://www.ncbi.nlm.nih.gov/pubmed/27680214
http://dx.doi.org/10.1186/s12929-016-0282-z