Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in idiopathic pulmonary fibrosis: A new ray of hope!

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with median survival of 2–3 years. It is described as fibroproliferative rather than pro-inflammatory disorder with limited treatment options. IPF diagnostics and therapeutics are a hot topic of current research. We descr...

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Detalles Bibliográficos
Autores principales: Desai, Unnati, Karkhanis, Vinaya S., Basu, Sandip, Joshi, Jyotsna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041417/
https://www.ncbi.nlm.nih.gov/pubmed/27833314
http://dx.doi.org/10.4103/0972-3919.187456
Descripción
Sumario:Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with median survival of 2–3 years. It is described as fibroproliferative rather than pro-inflammatory disorder with limited treatment options. IPF diagnostics and therapeutics are a hot topic of current research. We describe a case elaborating the utility of the whole body positron emission tomography with 2-deoxy-2-(fluorine-18) fluoro-D-glucose (F-18 FDG) integrated with computed tomography technique in IPF. The area of most intense pulmonary F--18 FDG uptake corresponded to regions of honeycombing suggesting metabolically active disease amenable to pharmacologic intervention. Additional F--18 FDG uptake was seen in mediastinal nodes implying an extrapulmonary component of disease.

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