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Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer

BACKGROUND: Cancer immunotherapy can be potentiated by conditioning regimens such as cyclophosphamide, which reduces the level of regulatory T cells (tregs). However, myeloid suppressive cells are still remaining. Accordingly to previous reports, gemcitabine improves immune status of cancer patients...

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Detalles Bibliográficos
Autores principales:	Eriksson, Emma, Wenthe, Jessica, Irenaeus, Sandra, Loskog, Angelica, Ullenhag, Gustav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041438/ https://www.ncbi.nlm.nih.gov/pubmed/27687804 http://dx.doi.org/10.1186/s12967-016-1037-z

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