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A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor

A whole-cell biosensor utilizing a transcription factor (TF) is an effective tool for sensitive and selective detection of specialty chemicals or anthropogenic molecules, but requires access to an expanded repertoire of TFs. Using homology modeling and ligand docking for binding pocket identificatio...

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Detalles Bibliográficos
Autores principales:	Jha, Ramesh K., Kern, Theresa L., Kim, Youngchang, Tesar, Christine, Jedrzejczak, Robert, Joachimiak, Andrzej, Strauss, Charlie E. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041483/ https://www.ncbi.nlm.nih.gov/pubmed/27536006 http://dx.doi.org/10.1093/nar/gkw687

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