Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism

Trpv5 plays an important role in calcium (Ca(2+)) homeostasis, among others by mediating renal calcium reabsorption. Accordingly, Trpv5 deficiency strongly stresses Ca(2+) homeostasis in order to maintain stable serum Ca(2+). We addressed the impact of lifelong challenge of calcium homeostasis on th...

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Detalles Bibliográficos
Autores principales: van der Eerden, Bram C.J., Koek, W. Nadia H., Roschger, Paul, Zillikens, M. Carola, Waarsing, Jan H., van der Kemp, Annemiete, Schreuders-Koedam, Marijke, Fratzl-Zelman, Nadja, Leenen, Pieter J.M., Hoenderop, Joost G.J., Klaushofer, Klaus, Bindels, René J.M., van Leeuwen, Johannes P.T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041880/
https://www.ncbi.nlm.nih.gov/pubmed/27102152
http://dx.doi.org/10.18632/oncotarget.8779

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