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CLEC4C p.K210del variant causes impaired cell surface transport in plasmacytoid dendritic cells of amyotrophic lateral sclerosis
The type II C-type lectin CLEC4C is a transmembrane protein selectively expressed on plasmacytoid dendritic cells (PDCs). Although its mechanism of action remains unclear, triggering of the extracellular C-terminal C-type carbohydrate recognition region of CLEC4C regulates the secretion of proinflam...
Autores principales: | Lim, Su Min, Kim, Young-Eun, Choi, Won Jun, Oh, Ki-Wook, Noh, Min-Young, Kwon, Min-Soo, Nahm, Minyeop, Kim, Namshin, Ki, Chang-Seok, Kim, Seung Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041881/ https://www.ncbi.nlm.nih.gov/pubmed/26943047 http://dx.doi.org/10.18632/oncotarget.7886 |
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