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Down-regulating cyclin-dependent kinase 9 of alloreactive CD4(+) T cells prolongs allograft survival

CDK9 (Cyclin-dependent kinase 9)/Cyclin T1/RNA polymerase II pathway has been demonstrated to promote the development of several inflammatory diseases, such as arthritis or atherosclerosis, however, its roles in allotransplantation rejection have not been addressed. Here, we found that CDK9/Cyclin T...

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Detalles Bibliográficos
Autores principales: Zhan, Yang, Han, Yeming, Sun, Hukui, Liang, Ting, Zhang, Chao, Song, Jing, Hou, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041884/
https://www.ncbi.nlm.nih.gov/pubmed/27102157
http://dx.doi.org/10.18632/oncotarget.8804

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