Cargando…

Down-regulating cyclin-dependent kinase 9 of alloreactive CD4(+) T cells prolongs allograft survival

CDK9 (Cyclin-dependent kinase 9)/Cyclin T1/RNA polymerase II pathway has been demonstrated to promote the development of several inflammatory diseases, such as arthritis or atherosclerosis, however, its roles in allotransplantation rejection have not been addressed. Here, we found that CDK9/Cyclin T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhan, Yang, Han, Yeming, Sun, Hukui, Liang, Ting, Zhang, Chao, Song, Jing, Hou, Guihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041884/ https://www.ncbi.nlm.nih.gov/pubmed/27102157 http://dx.doi.org/10.18632/oncotarget.8804

Ejemplares similares

An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8(+) T Cells
por: Wang, Wei, et al.
Publicado: (2017)

Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation
por: Han, Yeming, et al.
Publicado: (2015)

Shikonin Prolongs Allograft Survival via Induction of CD4(+)FoxP3(+) Regulatory T Cells
por: Zeng, Qiaohuang, et al.
Publicado: (2019)

Metabolic Pathways in Alloreactive T Cells
por: Brown, Rebecca A., et al.
Publicado: (2020)

In Utero Exposure to Exosomal and B-Cell Alloantigens Lessens Alloreactivity of Recipients’ Lymphocytes Rather than Confers Allograft Tolerance
por: Chen, Jeng-Chang, et al.
Publicado: (2018)

Donor selection for KIR alloreactivity is associated with superior survival in haploidentical transplant with PTCy
por: Zou, Jun, et al.
Publicado: (2022)

CD8+CD122+PD-1+ Tregs Synergize With Costimulatory Blockade of CD40/CD154, but Not B7/CD28, to Prolong Murine Allograft Survival
por: Liu, Huazhen, et al.
Publicado: (2019)

Antibody-Dependent NK Cell Activation Is Associated with Late Kidney Allograft Dysfunction and the Complement-Independent Alloreactive Potential of Donor-Specific Antibodies
por: Legris, Tristan, et al.
Publicado: (2016)

Artemisinin Attenuates Transplant Rejection by Inhibiting Multiple Lymphocytes and Prolongs Cardiac Allograft Survival
por: Yang, Zhe, et al.
Publicado: (2021)

CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response
por: Bettens, Florence, et al.
Publicado: (2021)

Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry
por: Juvet, Stephen C., et al.
Publicado: (2017)

Berberine Prolongs Mouse Heart Allograft Survival by Activating T Cell Apoptosis via the Mitochondrial Pathway
por: Ma, Yunhan, et al.
Publicado: (2021)

Donor-Specific Regulatory T Cells Acquired from Tolerant Mice Bearing Cardiac Allograft Promote Mixed Chimerism and Prolong Intestinal Allograft Survival
por: Shen, Xiao-Fei, et al.
Publicado: (2016)

Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4(+) Foxp3(−) T Cells into CD4(+) Foxp3(+) Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival
por: Oyarce, Karina, et al.
Publicado: (2018)

Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NF-κB/NLRP3 Pathway
por: Du, Xiaoxiao, et al.
Publicado: (2021)

Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival
por: Cheng, Pengrui, et al.
Publicado: (2023)

IL-2-Mediated In Vivo Expansion of Regulatory T Cells Combined with CD154–CD40 Co-Stimulation Blockade but Not CTLA-4 Ig Prolongs Allograft Survival in Naive and Sensitized Mice
por: Govender, Lerisa, et al.
Publicado: (2017)

Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance
por: Ruiz, Paulina, et al.
Publicado: (2015)

Inhibition of Autophagy Prolongs Recipient Survival Through Promoting CD8(+) T Cell Apoptosis in a Rat Liver Transplantation Model
por: Chen, Xiaolong, et al.
Publicado: (2019)

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice
por: Mangada, Julie, et al.
Publicado: (2009)

Dendritic Cells Transduced with Single Immunoglobulin IL-1-Related Receptor Exhibit Immature Properties and Prolong Islet Allograft Survival
por: Xue, Zhicheng, et al.
Publicado: (2017)

Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4(+) T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation
por: Hadjis, Ashley D., et al.
Publicado: (2022)

Hidden Patterns of Anti-HLA Class I Alloreactivity Revealed Through Machine Learning
por: Vittoraki, Angeliki G., et al.
Publicado: (2021)

Cyclic Helix B Peptide Prolongs Skin Allograft Survival via Inhibition of B Cell Immune Responses in a Murine Model
por: Zheng, Long, et al.
Publicado: (2021)

Commentary: Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4+ T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation
por: Stokes, Jessica, et al.
Publicado: (2022)

Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential
por: Bronk, Crystina C., et al.
Publicado: (2012)

Culture-Expanded Human Invariant Natural Killer T Cells Suppress T-Cell Alloreactivity and Eradicate Leukemia
por: Schmid, Hannes, et al.
Publicado: (2018)

High Throughput Human T Cell Receptor Sequencing: A New Window Into Repertoire Establishment and Alloreactivity
por: Fu, Jianing, et al.
Publicado: (2021)

Clonal dynamics of alloreactive T cells in kidney allograft rejection after anti-PD-1 therapy
por: Dunlap, Garrett S., et al.
Publicado: (2023)

Mechanisms of Immune Tolerance in Liver Transplantation-Crosstalk Between Alloreactive T Cells and Liver Cells With Therapeutic Prospects
por: Lei, Hong, et al.
Publicado: (2019)

Identification and Tracking of Alloreactive T Cell Clones in Rhesus Macaques Through the RM-scTCR-Seq Platform
por: Gerdemann, Ulrike, et al.
Publicado: (2022)

Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death
por: Molina, Megan S., et al.
Publicado: (2021)

Comparison of NK alloreactivity prediction models based on KIR-MHC interactions in haematopoietic stem cell transplantation
por: Dhuyser, Adèle, et al.
Publicado: (2023)

Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival
Publicado: (1994)

C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection
por: Goutaudier, Valentin, et al.
Publicado: (2019)

Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft
por: Jalili, Reza B., et al.
Publicado: (2010)

Prolonged Survival of Allografts Induced by Mycobacterial Hsp70 Is Dependent on CD4+CD25+ Regulatory T Cells
por: Borges, Thiago J., et al.
Publicado: (2010)

Cyclin-dependent kinase 9 is required for the survival of adult Drosophila melanogaster glia
por: Foo, Lynette C.
Publicado: (2017)

Alloreactivity of Virus-Specific T Cells: Possible Implication of Graft-Versus-Host Disease and Graft-Versus-Leukemia Effects
por: Fuji, Shigeo, et al.
Publicado: (2013)

Alloreactive Natural Killer Cells for the Treatment of Acute Myeloid Leukemia: From Stem Cell Transplantation to Adoptive Immunotherapy
por: Ruggeri, Loredana, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2riskv7d8nacoaar9qmv8tqetc