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Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin
The sphingolipid metabolising enzyme Acid Sphingomyelinase (A-SMase) has been recently shown to inhibit melanoma progression and correlate inversely to tumour grade. In this study we have investigated the role of A-SMase in the chemo-resistance to anticancer treatmentusing mice with melanoma allogra...
Autores principales: | Cervia, Davide, Assi, Emma, De Palma, Clara, Giovarelli, Matteo, Bizzozero, Laura, Pambianco, Sarah, Di Renzo, Ilaria, Zecchini, Silvia, Moscheni, Claudia, Vantaggiato, Chiara, Procacci, Patrizia, Clementi, Emilio, Perrotta, Cristiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041885/ https://www.ncbi.nlm.nih.gov/pubmed/27107419 http://dx.doi.org/10.18632/oncotarget.8735 |
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