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Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways
Fascin-1, an actin-bundling protein, plays an important role in cancer cell migration and invasion; however, the underlying mechanism remains unclear. On the basis of a 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced cell migration model, it was shown that TPA increased fascin-1 mRNA and protein...
Autores principales: | Lii, Chong-Kuei, Chang, Jer-Wei, Chen, Jia-Jing, Chen, Haw-Wen, Liu, Kai-Li, Yeh, Shu-Lan, Wang, Tsu-Shing, Liu, Shu-Hui, Tsai, Chia-Han, Li, Chien-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041895/ https://www.ncbi.nlm.nih.gov/pubmed/27036017 http://dx.doi.org/10.18632/oncotarget.7301 |
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