Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients

PURPOSE: This phase I trial aimed to assess the safety and determine the recommended Phase II dose (RP2D) of Cidofovir combined with chemoradiotherapy in patients with stage IB2-IVA cervical cancer. EXPERIMENTAL DESIGN: Incremental doses (1, 2.5, 5 and 6.5 mg/kg) of IV Cidofovir were administered we...

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Detalles Bibliográficos
Autores principales: Deutsch, Eric, Haie-Meder, Christine, Bayar, Mohamed Amine, Mondini, Michele, Laporte, Mélanie, Mazeron, Renaud, Adam, Julien, Varga, Andrea, Vassal, Gilles, Magné, Nicolas, Chargari, Cyrus, Lanoy, Emilie, Pautier, Patricia, Levy, Antonin, Soria, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041925/
https://www.ncbi.nlm.nih.gov/pubmed/27016411
http://dx.doi.org/10.18632/oncotarget.8224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041925/
https://www.ncbi.nlm.nih.gov/pubmed/27016411
http://dx.doi.org/10.18632/oncotarget.8224

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