Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages

Liver metastasis accounts for many of the cancer deaths in patients. Effective treatment for metastatic liver tumors is not available. Here, we provide evidence for the role of miR-18a in the induction of liver M1 (F4/80(+)interferon gamma (IFNγ)(+)IL-12(+)) macrophages. We found that miR-18a encaps...

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Detalles Bibliográficos
Autores principales: Teng, Yun, Mu, Jingyao, Hu, Xin, Samykutty, Abhilash, Zhuang, Xiaoying, Deng, Zhongbin, Zhang, Lifeng, Cao, Pengxiao, Yan, Jun, Miller, Donald, Zhang, Huang-Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041936/
https://www.ncbi.nlm.nih.gov/pubmed/27028860
http://dx.doi.org/10.18632/oncotarget.8361

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