Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

We have recently shown that rs2304277 variant in the OGG1 glycosidase gene of the Base Excision Repair pathway can increase ovarian cancer risk in BRCA1 mutation carriers. In the present study, we aimed to explore the role of this genetic variant on different genome instability hallmarks to explain...

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Detalles Bibliográficos
Autores principales: Benitez-Buelga, Carlos, Vaclová, Tereza, Ferreira, Sofia, Urioste, Miguel, Inglada-Perez, Lucia, Soberón, Nora, Blasco, Maria A., Osorio, Ana, Benitez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041946/
https://www.ncbi.nlm.nih.gov/pubmed/27015555
http://dx.doi.org/10.18632/oncotarget.8272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041946/
https://www.ncbi.nlm.nih.gov/pubmed/27015555
http://dx.doi.org/10.18632/oncotarget.8272

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