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Loss of HIF-1β in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

Activation of hypoxia-inducible factor (HIF) and macrophage infiltration of solid tumors independently promote tumor progression. As little is known how myeloid HIF affects tumor development, we injected the polycyclic aromatic hydrocarbon (PAH) and procarcinogen 3-methylcholanthrene (MCA; 100 μg/10...

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Detalles Bibliográficos
Autores principales:	Henke, Nina, Ferreirós, Nerea, Geisslinger, Gerd, Ding, Martina G., Essler, Silke, Fuhrmann, Dominik C., Geis, Theresa, Namgaladze, Dmitry, Dehne, Nathalie, Brüne, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041954/ https://www.ncbi.nlm.nih.gov/pubmed/27015123 http://dx.doi.org/10.18632/oncotarget.8297

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