Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis

Glioma-associated oncogene 2 (Gli2), a primary transcriptional regulator of Hedgehog (Hh) signaling, is essential for hepatocellular carcinoma (HCC) growth and survival. However, the underlying molecular mechanism and crucial downstream targets of Gli2 in human HCC are not fully understood. Here, we...

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Detalles Bibliográficos
Autores principales: Shi, Chao, Huang, Dengliang, Lu, Nonghua, Chen, Dan, Zhang, Minhong, Yan, Yehong, Deng, Libin, Lu, Quqin, Lu, Hua, Luo, Shiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041975/
https://www.ncbi.nlm.nih.gov/pubmed/27036048
http://dx.doi.org/10.18632/oncotarget.8441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041975/
https://www.ncbi.nlm.nih.gov/pubmed/27036048
http://dx.doi.org/10.18632/oncotarget.8441

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