Cargando…
Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis
Glioma-associated oncogene 2 (Gli2), a primary transcriptional regulator of Hedgehog (Hh) signaling, is essential for hepatocellular carcinoma (HCC) growth and survival. However, the underlying molecular mechanism and crucial downstream targets of Gli2 in human HCC are not fully understood. Here, we...
Autores principales: | Shi, Chao, Huang, Dengliang, Lu, Nonghua, Chen, Dan, Zhang, Minhong, Yan, Yehong, Deng, Libin, Lu, Quqin, Lu, Hua, Luo, Shiwen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041975/ https://www.ncbi.nlm.nih.gov/pubmed/27036048 http://dx.doi.org/10.18632/oncotarget.8441 |
Ejemplares similares
-
FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression
por: Hu, Guohui, et al.
Publicado: (2019) -
Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway
por: Zhou, Fen, et al.
Publicado: (2016) -
SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer
por: Zeng, Chunyan, et al.
Publicado: (2014) -
Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling
por: Chen, Qi, et al.
Publicado: (2014) -
Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells
por: Wang, DeJie, et al.
Publicado: (2017)