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E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair

Nucleotide excision repair (NER) is a major mechanism for removal of DNA lesions induced by exposure to UV radiation in the epidermis. Recognition of damaged DNA sites is the initial step in their repair, and requires multiprotein complexes that contain XPC and hHR23 proteins, or their orthologues....

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Detalles Bibliográficos
Autores principales: Singh, Randeep K., Dagnino, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041980/
https://www.ncbi.nlm.nih.gov/pubmed/27028861
http://dx.doi.org/10.18632/oncotarget.8362