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A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells

The signaling lymphocyte activation molecule family [SLAMF] of cell surface receptors partakes in both the development of several immunocyte lineages and innate and adaptive immune responses in humans and mice. For instance, the homophilic molecule SLAMF6 (CD352) is in part involved in natural kille...

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Detalles Bibliográficos
Autores principales: Yigit, Burcu, Halibozek, Peter J., Chen, Shih-Shih, O'Keeffe, Michael S., Arnason, Jon, Avigan, David, Gattei, Valter, Bhan, Atul, Cen, Osman, Longnecker, Richard, Chiorazzi, Nicholas, Wang, Ninghai, Engel, Pablo, Terhorst, Cox
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041984/
https://www.ncbi.nlm.nih.gov/pubmed/27029059
http://dx.doi.org/10.18632/oncotarget.8378

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