RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma

N-Myc downstream-regulated gene 2 (NDRG2) protein is a tumor suppressor that inhibits cancer growth, metastasis and invasion. The ubiquitin ligase RNF4 integrates signaling by SUMO and ubiquitin through its selective recognition and ubiquitination of SUMO-modified proteins. We evaluated NDRG2 SUMOyl...

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Detalles Bibliográficos
Autores principales: Tantai, Jicheng, Pan, Xufeng, Hu, Dingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042018/
https://www.ncbi.nlm.nih.gov/pubmed/27072586
http://dx.doi.org/10.18632/oncotarget.8663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042018/
https://www.ncbi.nlm.nih.gov/pubmed/27072586
http://dx.doi.org/10.18632/oncotarget.8663

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