Genotoxicity of three food processing contaminants in transgenic mice expressing human sulfotransferases 1A1 and 1A2 as assessed by the in vivo alkaline single cell gel electrophoresis assay

The food processing contaminants 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), 5‐hydroxymethylfurfural (HMF) and 2,5 dimethylfuran (DMF) are potentially both mutagenic and carcinogenic in vitro and/or in vivo, although data on DMF is lacking. The PHIP metabolite N‐hydroxy‐PhIP and HMF are...

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Detalles Bibliográficos
Autores principales: Høie, Anja Hortemo, Svendsen, Camilla, Brunborg, Gunnar, Glatt, Hansruedi, Alexander, Jan, Meinl, Walter, Husøy, Trine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042101/
https://www.ncbi.nlm.nih.gov/pubmed/26270892
http://dx.doi.org/10.1002/em.21963

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