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Primary transmission of chronic wasting disease versus scrapie prions from small ruminants to transgenic mice expressing ovine or cervid prion protein

Development of mice expressing either ovine (Tg338) or cervid (TgElk) prion protein (PrP) have aided in characterization of scrapie and chronic wasting disease (CWD), respectively. Experimental inoculation of sheep with CWD prions has demonstrated the potential for interspecies transmission but, inf...

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Detalles Bibliográficos
Autores principales:	Madsen-Bouterse, Sally A., Schneider, David A., Zhuang, Dongyue, Dassanayake, Rohana P., Balachandran, Aru, Mitchell, Gordon B., O'Rourke, Katherine I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2016
Materias:	Standard
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042132/ https://www.ncbi.nlm.nih.gov/pubmed/27393736 http://dx.doi.org/10.1099/jgv.0.000539

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