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A unified statistical model of protein multiple sequence alignment integrating direct coupling and insertions

The multiple sequence alignment (MSA) of a protein family provides a wealth of information in terms of the conservation pattern of amino acid residues not only at each alignment site but also between distant sites. In order to statistically model the MSA incorporating both short-range and long-range...

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Detalles Bibliográficos
Autor principal: Kinjo, Akira R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042171/
https://www.ncbi.nlm.nih.gov/pubmed/27924257
http://dx.doi.org/10.2142/biophysico.13.0_45