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A unified statistical model of protein multiple sequence alignment integrating direct coupling and insertions
The multiple sequence alignment (MSA) of a protein family provides a wealth of information in terms of the conservation pattern of amino acid residues not only at each alignment site but also between distant sites. In order to statistically model the MSA incorporating both short-range and long-range...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Biophysical Society of Japan (BSJ)
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042171/ https://www.ncbi.nlm.nih.gov/pubmed/27924257 http://dx.doi.org/10.2142/biophysico.13.0_45 |