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Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments

BACKGROUND & AIMS: Crohn’s Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when activated intestinal fibroblasts deposit excessive amounts of extracellular matrix (ECM) in affected areas. A major component of the ECM is...

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Detalles Bibliográficos
Autores principales:	Soroosh, Artin, Albeiroti, Sami, West, Gail A., Willard, Belinda, Fiocchi, Claudio, de la Motte, Carol A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042354/ https://www.ncbi.nlm.nih.gov/pubmed/27981209 http://dx.doi.org/10.1016/j.jcmgh.2015.12.007

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