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Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice

We previously demonstrated that the sodium/hydrogen exchanger NHA2, also known as NHEDC2 or SLC9B2, is critical for insulin secretion by β–cells. To gain more insights into the role of NHA2 on systemic glucose homeostasis, we studied the impact of loss of NHA2 during the physiological aging process...

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Detalles Bibliográficos
Autores principales: Deisl, Christine, Anderegg, Manuel, Albano, Giuseppe, Lüscher, Benjamin P., Cerny, David, Soria, Rodrigo, Bouillet, Elisa, Rimoldi, Stefano, Scherrer, Urs, Fuster, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042380/
https://www.ncbi.nlm.nih.gov/pubmed/27685945
http://dx.doi.org/10.1371/journal.pone.0163568