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Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of “Difficult-to-Express” Proteins and Future Perspectives

Nowadays, biotechnological processes play a pivotal role in target protein production. In this context, Chinese Hamster Ovary (CHO) cells are one of the most prominent cell lines for the expression of recombinant proteins and revealed as a safe host for nearly 40 years. Nevertheless, the major bottl...

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Detalles Bibliográficos
Autores principales:	Thoring, Lena, Wüstenhagen, Doreen A., Borowiak, Maria, Stech, Marlitt, Sonnabend, Andrei, Kubick, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042383/ https://www.ncbi.nlm.nih.gov/pubmed/27684475 http://dx.doi.org/10.1371/journal.pone.0163670

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