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Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea
T:G base pair arising from spontaneous deamination of 5mC or polymerase errors is a great challenge for DNA repair of hyperthermophilic archaea, especially Crenarchaea. Most strains in this phylum lack the protein homologues responsible for the recognition of the mismatch in the DNA repair pathways....
Autores principales: | Tian, Lei, Zhang, Zhenfeng, Wang, Hanqian, Zhao, Mohan, Dong, Yuhui, Gong, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042384/ https://www.ncbi.nlm.nih.gov/pubmed/27685992 http://dx.doi.org/10.1371/journal.pone.0163361 |
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