Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model

Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability. The cognitive deficits in the mouse model for this disorder, the Fragile X Mental Retardation 1 (Fmr1) knockout (KO) mouse, have been restored by different pharmacological approaches, among those the blockade o...

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Detalles Bibliográficos
Autores principales: Gomis-González, Maria, Busquets-Garcia, Arnau, Matute, Carlos, Maldonado, Rafael, Mato, Susana, Ozaita, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042387/
https://www.ncbi.nlm.nih.gov/pubmed/27589806
http://dx.doi.org/10.3390/genes7090056

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