Telomerase Regulation from Beginning to the End

The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex...

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Detalles Bibliográficos
Autores principales: MacNeil, Deanna Elise, Bensoussan, Hélène Jeanne, Autexier, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042394/
https://www.ncbi.nlm.nih.gov/pubmed/27649246
http://dx.doi.org/10.3390/genes7090064
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author MacNeil, Deanna Elise
Bensoussan, Hélène Jeanne
Autexier, Chantal
author_facet MacNeil, Deanna Elise
Bensoussan, Hélène Jeanne
Autexier, Chantal
author_sort MacNeil, Deanna Elise
collection PubMed
description The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex and function at its site of action, emphasizing new developments and how they contribute to the foundational knowledge of telomerase and telomere biology.
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spelling pubmed-50423942016-09-29 Telomerase Regulation from Beginning to the End MacNeil, Deanna Elise Bensoussan, Hélène Jeanne Autexier, Chantal Genes (Basel) Review The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex and function at its site of action, emphasizing new developments and how they contribute to the foundational knowledge of telomerase and telomere biology. MDPI 2016-09-14 /pmc/articles/PMC5042394/ /pubmed/27649246 http://dx.doi.org/10.3390/genes7090064 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
MacNeil, Deanna Elise
Bensoussan, Hélène Jeanne
Autexier, Chantal
Telomerase Regulation from Beginning to the End
title Telomerase Regulation from Beginning to the End
title_full Telomerase Regulation from Beginning to the End
title_fullStr Telomerase Regulation from Beginning to the End
title_full_unstemmed Telomerase Regulation from Beginning to the End
title_short Telomerase Regulation from Beginning to the End
title_sort telomerase regulation from beginning to the end
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042394/
https://www.ncbi.nlm.nih.gov/pubmed/27649246
http://dx.doi.org/10.3390/genes7090064
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AT bensoussanhelenejeanne telomeraseregulationfrombeginningtotheend
AT autexierchantal telomeraseregulationfrombeginningtotheend

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