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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042396/ https://www.ncbi.nlm.nih.gov/pubmed/27657132 http://dx.doi.org/10.3390/genes7090066 |