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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...

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Detalles Bibliográficos
Autores principales:	Amorim, João P., Santos, Gustavo, Vinagre, João, Soares, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042396/ https://www.ncbi.nlm.nih.gov/pubmed/27657132 http://dx.doi.org/10.3390/genes7090066

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