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DNA Polymerase θ: A Unique Multifunctional End-Joining Machine

The gene encoding DNA polymerase θ (Polθ) was discovered over ten years ago as having a role in suppressing genome instability in mammalian cells. Studies have now clearly documented an essential function for this unique A-family polymerase in the double-strand break (DSB) repair pathway alternative...

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Detalles Bibliográficos
Autores principales:	Black, Samuel J., Kashkina, Ekaterina, Kent, Tatiana, Pomerantz, Richard T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042397/ https://www.ncbi.nlm.nih.gov/pubmed/27657134 http://dx.doi.org/10.3390/genes7090067

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