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Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

Hypochlorous acid (HOCl) is produced naturally by neutrophils and other cells to kill conventional microbes in vivo. Synthetic preparations containing HOCl can also be effective as microbial disinfectants. Here we have tested whether HOCl can also inactivate prions and other self-propagating protein...

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Detalles Bibliográficos
Autores principales:	Hughson, Andrew G., Race, Brent, Kraus, Allison, Sangaré, Laura R., Robins, Lori, Groveman, Bradley R., Saijo, Eri, Phillips, Katie, Contreras, Luis, Dhaliwal, Virkamal, Manca, Matteo, Zanusso, Gianluigi, Terry, Daniel, Williams, Jeffrey F., Caughey, Byron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042475/ https://www.ncbi.nlm.nih.gov/pubmed/27685252 http://dx.doi.org/10.1371/journal.ppat.1005914

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