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Agmatine Reduces Lipopolysaccharide-Mediated Oxidant Response via Activating PI3K/Akt Pathway and Up-Regulating Nrf2 and HO-1 Expression in Macrophages

Macrophages are key responders of inflammation and are closely related with oxidative stress. Activated macrophages can enhance oxygen depletion, which causes an overproduction of reactive oxygen species (ROS) and leads to further excessive inflammatory response and tissue damage. Agmatine, an endog...

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Detalles Bibliográficos
Autores principales:	Chai, Jianshen, Luo, Li, Hou, Fengyan, Fan, Xia, Yu, Jing, Ma, Wei, Tang, Wangqi, Yang, Xue, Zhu, Junyu, Kang, Wenyuan, Yan, Jun, Liang, Huaping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042521/ https://www.ncbi.nlm.nih.gov/pubmed/27685463 http://dx.doi.org/10.1371/journal.pone.0163634

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