Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

Memories are assumed to be formed by sets of synapses changing their structural or functional performance. The efficacy of forming new memories declines with advancing age, but the synaptic changes underlying age-induced memory impairment remain poorly understood. Recently, we found spermidine feedi...

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Detalles Bibliográficos
Autores principales: Gupta, Varun K., Pech, Ulrike, Bhukel, Anuradha, Fulterer, Andreas, Ender, Anatoli, Mauermann, Stephan F., Andlauer, Till F. M., Antwi-Adjei, Emmanuel, Beuschel, Christine, Thriene, Kerstin, Maglione, Marta, Quentin, Christine, Bushow, René, Schwärzel, Martin, Mielke, Thorsten, Madeo, Frank, Dengjel, Joern, Fiala, André, Sigrist, Stephan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042543/
https://www.ncbi.nlm.nih.gov/pubmed/27684064
http://dx.doi.org/10.1371/journal.pbio.1002563

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