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Ketamine Sedation in Gastrointestinal Endoscopy in Children

BACKGROUND: Moderate sedation for gastrointestinal endoscopy has traditionally been provided by the endoscopist. Controversy has ensued over safe and efficient sedation practice as endoscopy has increased in numbers and complexity. AIM: To evaluate the safety of ketamine sedation given by non-anesth...

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Autores principales: Eskander, Ayman E., Baroudy, Nevine R. El, Refay, Amira S. El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042621/
https://www.ncbi.nlm.nih.gov/pubmed/27703561
http://dx.doi.org/10.3889/oamjms.2016.085
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author Eskander, Ayman E.
Baroudy, Nevine R. El
Refay, Amira S. El
author_facet Eskander, Ayman E.
Baroudy, Nevine R. El
Refay, Amira S. El
author_sort Eskander, Ayman E.
collection PubMed
description BACKGROUND: Moderate sedation for gastrointestinal endoscopy has traditionally been provided by the endoscopist. Controversy has ensued over safe and efficient sedation practice as endoscopy has increased in numbers and complexity. AIM: To evaluate the safety of ketamine sedation given by non-anesthesiologist during gastrointestinal endoscopy in children. METHODS: A prospective study of 100 paediatric patients with gastrointestinal symptoms who were a candidate for upper or lower gastrointestinal endoscopy in paediatric endoscopy unit at Abo El-Reesh Paediatric Hospital, Cairo University. All children were > 2 years old and weighed > 6 kg. The analysis was performed in terms of sedation-related complications. RESULTS: A total 100 paediatric patients including 53 males and 47 females with mean age of 5.04 years were involved in the study. All children were medicated with ketamine with a mean dose of 3.77mg/kg. No complications occurred in 87% of cases. Desaturation occurred in 13% of the cases and was reversible by supplemental nasal oxygen. Desaturation was more frequent during Upper GI Endoscopy and with the intramuscular route (p value=0.049). No apnea, bradycardia, arrest or emergence reactions were recorded. CONCLUSION: Ketamine sedation found to be safe for paediatric gastrointestinal endoscopy in Egyptian children without co-morbidities. Transient Hypoxia (13%) may occur but easily reversed by nasal oxygen therapy.
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spelling pubmed-50426212016-10-04 Ketamine Sedation in Gastrointestinal Endoscopy in Children Eskander, Ayman E. Baroudy, Nevine R. El Refay, Amira S. El Open Access Maced J Med Sci Clinical Science BACKGROUND: Moderate sedation for gastrointestinal endoscopy has traditionally been provided by the endoscopist. Controversy has ensued over safe and efficient sedation practice as endoscopy has increased in numbers and complexity. AIM: To evaluate the safety of ketamine sedation given by non-anesthesiologist during gastrointestinal endoscopy in children. METHODS: A prospective study of 100 paediatric patients with gastrointestinal symptoms who were a candidate for upper or lower gastrointestinal endoscopy in paediatric endoscopy unit at Abo El-Reesh Paediatric Hospital, Cairo University. All children were > 2 years old and weighed > 6 kg. The analysis was performed in terms of sedation-related complications. RESULTS: A total 100 paediatric patients including 53 males and 47 females with mean age of 5.04 years were involved in the study. All children were medicated with ketamine with a mean dose of 3.77mg/kg. No complications occurred in 87% of cases. Desaturation occurred in 13% of the cases and was reversible by supplemental nasal oxygen. Desaturation was more frequent during Upper GI Endoscopy and with the intramuscular route (p value=0.049). No apnea, bradycardia, arrest or emergence reactions were recorded. CONCLUSION: Ketamine sedation found to be safe for paediatric gastrointestinal endoscopy in Egyptian children without co-morbidities. Transient Hypoxia (13%) may occur but easily reversed by nasal oxygen therapy. Institute of Immunobiology and Human Genetics 2016-09-15 2016-07-26 /pmc/articles/PMC5042621/ /pubmed/27703561 http://dx.doi.org/10.3889/oamjms.2016.085 Text en Copyright: © 2016 Ayman E. Eskander, Nevine R. El Baroudy, Amira S. El Refay. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Science
Eskander, Ayman E.
Baroudy, Nevine R. El
Refay, Amira S. El
Ketamine Sedation in Gastrointestinal Endoscopy in Children
title Ketamine Sedation in Gastrointestinal Endoscopy in Children
title_full Ketamine Sedation in Gastrointestinal Endoscopy in Children
title_fullStr Ketamine Sedation in Gastrointestinal Endoscopy in Children
title_full_unstemmed Ketamine Sedation in Gastrointestinal Endoscopy in Children
title_short Ketamine Sedation in Gastrointestinal Endoscopy in Children
title_sort ketamine sedation in gastrointestinal endoscopy in children
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042621/
https://www.ncbi.nlm.nih.gov/pubmed/27703561
http://dx.doi.org/10.3889/oamjms.2016.085
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