Cargando…

Role and Importance of Chlamydia Trachomatis in Pregnant Patients

AIM: The aim of this study was to assess the prevalence of chlamydial infection among pregnant women and to determine the role of this infection in the fetus. MATERIAL AND METHODS: In the first phase of this study were reported 58 pregnant women with a positive test for active chlamydial infection b...

Descripción completa

Detalles Bibliográficos
Autores principales: Angelova, Mariya, Kovachev, Emil, Tsankova, Veselina, Koleva, Iliana, Mangarova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042624/
https://www.ncbi.nlm.nih.gov/pubmed/27703564
http://dx.doi.org/10.3889/oamjms.2016.077
_version_ 1782456626296389632
author Angelova, Mariya
Kovachev, Emil
Tsankova, Veselina
Koleva, Iliana
Mangarova, Silvia
author_facet Angelova, Mariya
Kovachev, Emil
Tsankova, Veselina
Koleva, Iliana
Mangarova, Silvia
author_sort Angelova, Mariya
collection PubMed
description AIM: The aim of this study was to assess the prevalence of chlamydial infection among pregnant women and to determine the role of this infection in the fetus. MATERIAL AND METHODS: In the first phase of this study were reported 58 pregnant women with a positive test for active chlamydial infection by applying immunofluorescence. In the second phase of the study were reported pregnant with premature burst membranes (PBM), postnatal complications associated with chlamydial infection as puerperal endometritis, and newborns are monitored for low birth weight and growth retardation at birth. RESULTS: With a positive test are 58 patients in the first trimester or pregnancy registration in our consultation. After regimen with Sumamed (2 x 500 mg for three days and after 10 days again same scheme for them and their partner) at the beginning of the third trimester, the PCR test was made again. Of these, 5 were positive again, participants are between 20 and 30 years old. With premature rupture of OM are 20 patients. There was no increased incidence of premature births. Infants born to infected mothers have a higher risk of developing respiratory symptoms in the first 60 days of life. 3 of them have low for his age bodyweight. CONCLUSIONS: The scarcity of data on manifestations of chlamydial infection during pregnancy and neonatal outcomes justifies this study. Early diagnosis for registration of pregnancy and timely treatment of chlamydial infection as well as scrutinising the infection during the third trimester of pregnancy can prevent infection of the newborn. Therefore, preventive examinations should be considered as a priority for early detection of asymptomatic chlamydial infection in the conduct of antenatal care.
format Online
Article
Text
id pubmed-5042624
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Institute of Immunobiology and Human Genetics
record_format MEDLINE/PubMed
spelling pubmed-50426242016-10-04 Role and Importance of Chlamydia Trachomatis in Pregnant Patients Angelova, Mariya Kovachev, Emil Tsankova, Veselina Koleva, Iliana Mangarova, Silvia Open Access Maced J Med Sci Clinical Science AIM: The aim of this study was to assess the prevalence of chlamydial infection among pregnant women and to determine the role of this infection in the fetus. MATERIAL AND METHODS: In the first phase of this study were reported 58 pregnant women with a positive test for active chlamydial infection by applying immunofluorescence. In the second phase of the study were reported pregnant with premature burst membranes (PBM), postnatal complications associated with chlamydial infection as puerperal endometritis, and newborns are monitored for low birth weight and growth retardation at birth. RESULTS: With a positive test are 58 patients in the first trimester or pregnancy registration in our consultation. After regimen with Sumamed (2 x 500 mg for three days and after 10 days again same scheme for them and their partner) at the beginning of the third trimester, the PCR test was made again. Of these, 5 were positive again, participants are between 20 and 30 years old. With premature rupture of OM are 20 patients. There was no increased incidence of premature births. Infants born to infected mothers have a higher risk of developing respiratory symptoms in the first 60 days of life. 3 of them have low for his age bodyweight. CONCLUSIONS: The scarcity of data on manifestations of chlamydial infection during pregnancy and neonatal outcomes justifies this study. Early diagnosis for registration of pregnancy and timely treatment of chlamydial infection as well as scrutinising the infection during the third trimester of pregnancy can prevent infection of the newborn. Therefore, preventive examinations should be considered as a priority for early detection of asymptomatic chlamydial infection in the conduct of antenatal care. Institute of Immunobiology and Human Genetics 2016-09-15 2016-08-05 /pmc/articles/PMC5042624/ /pubmed/27703564 http://dx.doi.org/10.3889/oamjms.2016.077 Text en Copyright: © 2016 Mariya Angelova, Emil Kovachev, Veselina Tsankova, Iliana Koleva, Silvia Mangarova. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Science
Angelova, Mariya
Kovachev, Emil
Tsankova, Veselina
Koleva, Iliana
Mangarova, Silvia
Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title_full Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title_fullStr Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title_full_unstemmed Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title_short Role and Importance of Chlamydia Trachomatis in Pregnant Patients
title_sort role and importance of chlamydia trachomatis in pregnant patients
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042624/
https://www.ncbi.nlm.nih.gov/pubmed/27703564
http://dx.doi.org/10.3889/oamjms.2016.077
work_keys_str_mv AT angelovamariya roleandimportanceofchlamydiatrachomatisinpregnantpatients
AT kovachevemil roleandimportanceofchlamydiatrachomatisinpregnantpatients
AT tsankovaveselina roleandimportanceofchlamydiatrachomatisinpregnantpatients
AT kolevailiana roleandimportanceofchlamydiatrachomatisinpregnantpatients
AT mangarovasilvia roleandimportanceofchlamydiatrachomatisinpregnantpatients