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Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet–Induced Liver Disease

BACKGROUND & AIMS: Innate immune dysfunction can promote chronic inflammatory diseases of the liver. For example, mice lacking the flagellin receptor Toll-like receptor 5 (TLR5) show microbial dysbiosis and predisposition to high-fat diet (HFD)-induced hepatic steatosis. The extent to which hepa...

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Detalles Bibliográficos
Autores principales:	Etienne-Mesmin, Lucie, Vijay-Kumar, Matam, Gewirtz, Andrew T., Chassaing, Benoit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042709/ https://www.ncbi.nlm.nih.gov/pubmed/28090564 http://dx.doi.org/10.1016/j.jcmgh.2016.04.007

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