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Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes
AIMS/HYPOTHESIS: Human pancreatic beta cells may be complicit in their own demise in type 1 diabetes, but how this occurs remains unclear. One potentially contributing factor is hyperexpression of HLA class I antigens. This was first described approximately 30 years ago, but has never been fully cha...
Autores principales: | Richardson, Sarah J., Rodriguez-Calvo, Teresa, Gerling, Ivan C., Mathews, Clayton E., Kaddis, John S., Russell, Mark A., Zeissler, Marie, Leete, Pia, Krogvold, Lars, Dahl-Jørgensen, Knut, von Herrath, Matthias, Pugliese, Alberto, Atkinson, Mark A., Morgan, Noel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042874/ https://www.ncbi.nlm.nih.gov/pubmed/27506584 http://dx.doi.org/10.1007/s00125-016-4067-4 |
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