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LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation

BACKGROUND & AIMS: The Lgr family of transmembrane proteins (Lgr4, 5, 6) act as functional receptors for R-spondin proteins (Rspo 1, 2, 3, 4), and potentiate Wnt signaling in different contexts. Lgr5 is arguably the best characterized of the Lgr family members in a number of adult and embryonic...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Hwai, Hill, David R., Kumar, Namit, Huang, Sha, Chin, Alana M., Dye, Briana R., Nagy, Melinda S., Verzi, Michael P., Spence, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042889/
https://www.ncbi.nlm.nih.gov/pubmed/28078320
http://dx.doi.org/10.1016/j.jcmgh.2016.06.002

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