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LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation
BACKGROUND & AIMS: The Lgr family of transmembrane proteins (Lgr4, 5, 6) act as functional receptors for R-spondin proteins (Rspo 1, 2, 3, 4), and potentiate Wnt signaling in different contexts. Lgr5 is arguably the best characterized of the Lgr family members in a number of adult and embryonic...
Autores principales: | Tsai, Yu-Hwai, Hill, David R., Kumar, Namit, Huang, Sha, Chin, Alana M., Dye, Briana R., Nagy, Melinda S., Verzi, Michael P., Spence, Jason R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042889/ https://www.ncbi.nlm.nih.gov/pubmed/28078320 http://dx.doi.org/10.1016/j.jcmgh.2016.06.002 |
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