Cargando…
Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria
BACKGROUND: Polypharmacy is commonly applied to elderly haemodialysis patients for treating terminal renal failure and multiple co-morbidities. Potentially inappropriate medications (PIMs) in multidrug regimens in geriatric populations can be identified using specially designed screening tools. OBJE...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042944/ https://www.ncbi.nlm.nih.gov/pubmed/27747833 http://dx.doi.org/10.1007/s40801-016-0088-z |
_version_ | 1782456670271569920 |
---|---|
author | Parker, Krystina Aasebø, Willy Stavem, Knut |
author_facet | Parker, Krystina Aasebø, Willy Stavem, Knut |
author_sort | Parker, Krystina |
collection | PubMed |
description | BACKGROUND: Polypharmacy is commonly applied to elderly haemodialysis patients for treating terminal renal failure and multiple co-morbidities. Potentially inappropriate medications (PIMs) in multidrug regimens in geriatric populations can be identified using specially designed screening tools. OBJECTIVE: The aims of this study were to estimate the prevalence of PIMs by applying the Screening Tool of Older Persons’ Prescriptions (STOPP) criteria and the Beers criteria to elderly haemodialysis patients and to assess the association of some risk factors with the presence of PIMs. METHODS: Fifty-one elderly haemodialysis patients participated; their median age was 74 (range 65–89) years, and 77 % of them were male. Demographic data, co-morbidity and medication lists were collected from the electronic medical records of the patients. The STOPP criteria were applied by two physicians independently to identify PIMs. The association of some risk factors with PIMs were assessed using Fisher’s exact test. RESULTS: The patients used a median of 13 (range 7–21) medications per day. The overall prevalence of PIMs using the STOPP criteria was 63 %, and using the Beers criteria was 43 %. The most prevalent PIMs were proton-pump inhibitors. Benzodiazepines and first-generation antihistamines were related to side effects such as falls in the previous 3 months, and calcium-channel blockers were associated with chronic constipation. The number of PIMs was not significantly associated with number of medications, age, sex and co-morbidity. CONCLUSIONS: The STOPP criteria revealed a high prevalence of PIMs in a population of elderly patients receiving haemodialysis. |
format | Online Article Text |
id | pubmed-5042944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-50429442016-10-14 Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria Parker, Krystina Aasebø, Willy Stavem, Knut Drugs Real World Outcomes Short Communication BACKGROUND: Polypharmacy is commonly applied to elderly haemodialysis patients for treating terminal renal failure and multiple co-morbidities. Potentially inappropriate medications (PIMs) in multidrug regimens in geriatric populations can be identified using specially designed screening tools. OBJECTIVE: The aims of this study were to estimate the prevalence of PIMs by applying the Screening Tool of Older Persons’ Prescriptions (STOPP) criteria and the Beers criteria to elderly haemodialysis patients and to assess the association of some risk factors with the presence of PIMs. METHODS: Fifty-one elderly haemodialysis patients participated; their median age was 74 (range 65–89) years, and 77 % of them were male. Demographic data, co-morbidity and medication lists were collected from the electronic medical records of the patients. The STOPP criteria were applied by two physicians independently to identify PIMs. The association of some risk factors with PIMs were assessed using Fisher’s exact test. RESULTS: The patients used a median of 13 (range 7–21) medications per day. The overall prevalence of PIMs using the STOPP criteria was 63 %, and using the Beers criteria was 43 %. The most prevalent PIMs were proton-pump inhibitors. Benzodiazepines and first-generation antihistamines were related to side effects such as falls in the previous 3 months, and calcium-channel blockers were associated with chronic constipation. The number of PIMs was not significantly associated with number of medications, age, sex and co-morbidity. CONCLUSIONS: The STOPP criteria revealed a high prevalence of PIMs in a population of elderly patients receiving haemodialysis. Springer International Publishing 2016-08-08 /pmc/articles/PMC5042944/ /pubmed/27747833 http://dx.doi.org/10.1007/s40801-016-0088-z Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Short Communication Parker, Krystina Aasebø, Willy Stavem, Knut Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title | Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title_full | Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title_fullStr | Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title_full_unstemmed | Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title_short | Potentially Inappropriate Medications in Elderly Haemodialysis Patients Using the STOPP Criteria |
title_sort | potentially inappropriate medications in elderly haemodialysis patients using the stopp criteria |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042944/ https://www.ncbi.nlm.nih.gov/pubmed/27747833 http://dx.doi.org/10.1007/s40801-016-0088-z |
work_keys_str_mv | AT parkerkrystina potentiallyinappropriatemedicationsinelderlyhaemodialysispatientsusingthestoppcriteria AT aasebøwilly potentiallyinappropriatemedicationsinelderlyhaemodialysispatientsusingthestoppcriteria AT stavemknut potentiallyinappropriatemedicationsinelderlyhaemodialysispatientsusingthestoppcriteria |