Rapid atrial pacing induces myocardial fibrosis by down-regulating Smad7 via microRNA-21 in rabbit

Tachycardia-induced atrial fibrosis is a hallmark of the structural remodeling of atrial fibrillation (AF). The mechanisms underlying tachycardia-induced atrial fibrosis remain unclear. In our previous study, we found that Smad7-downregulation promoted the development of atrial fibrosis in AF. Fibro...

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Detalles Bibliográficos
Autores principales: He, Xuyu, Zhang, Kunyi, Gao, Xiuren, Li, Liwen, Tan, Hong, Chen, Jiyan, Zhou, Yingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043001/
https://www.ncbi.nlm.nih.gov/pubmed/26968995
http://dx.doi.org/10.1007/s00380-016-0808-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043001/
https://www.ncbi.nlm.nih.gov/pubmed/26968995
http://dx.doi.org/10.1007/s00380-016-0808-z

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