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N-Methyl D-Aspartate Receptor Antagonist Kynurenic Acid Affects Human Cortical Development
Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan degradation, acts as an endogenous N-methyl-D-aspartate receptor (NMDAR) antagonist. Elevated levels of KYNA have been observed in pregnant women after viral infections and are considered to play a role in neurodevelopmental disorders. Ho...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043058/ https://www.ncbi.nlm.nih.gov/pubmed/27746712 http://dx.doi.org/10.3389/fnins.2016.00435 |