Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease

Neurofibrillary tangles composed of aggregates of hyperphosphorylated tau proteins are one of the neuropathological hallmarks of Alzheimer’s disease (AD) in addition to the deposition of β-amyloid plaques. Since the deposition of tau aggregates is closely associated with the severity of AD, the in v...

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Detalles Bibliográficos
Autores principales: Ono, Masahiro, Watanabe, Hiroyuki, Kitada, Ayane, Matsumura, Kenji, Ihara, Masafumi, Saji, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043239/
https://www.ncbi.nlm.nih.gov/pubmed/27687137
http://dx.doi.org/10.1038/srep34197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043239/
https://www.ncbi.nlm.nih.gov/pubmed/27687137
http://dx.doi.org/10.1038/srep34197

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