Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas

Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasio...

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Detalles Bibliográficos
Autores principales: Saito, Hiroyuki, Kashiyama, Hiroshi, Murohashi, Takashi, Sasaki, Kazunari, Misawa, Ryosuke, Ohwada, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Case and Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043253/
https://www.ncbi.nlm.nih.gov/pubmed/27721735
http://dx.doi.org/10.1159/000448878
Descripción
Sumario:Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasion. The patient underwent radical distal pancreatectomy and was subsequently treated with adjuvant chemotherapy using gemcitabine plus S-1 followed by maintenance chemotherapy with oral tegafur-uracil. The patient has been doing well with no evidence of recurrence for more than 6 years after surgery.

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