Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas

Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasio...

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Detalles Bibliográficos
Autores principales: Saito, Hiroyuki, Kashiyama, Hiroshi, Murohashi, Takashi, Sasaki, Kazunari, Misawa, Ryosuke, Ohwada, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Case and Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043253/
https://www.ncbi.nlm.nih.gov/pubmed/27721735
http://dx.doi.org/10.1159/000448878
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author Saito, Hiroyuki
Kashiyama, Hiroshi
Murohashi, Takashi
Sasaki, Kazunari
Misawa, Ryosuke
Ohwada, Susumu
author_facet Saito, Hiroyuki
Kashiyama, Hiroshi
Murohashi, Takashi
Sasaki, Kazunari
Misawa, Ryosuke
Ohwada, Susumu
author_sort Saito, Hiroyuki
collection PubMed
description Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasion. The patient underwent radical distal pancreatectomy and was subsequently treated with adjuvant chemotherapy using gemcitabine plus S-1 followed by maintenance chemotherapy with oral tegafur-uracil. The patient has been doing well with no evidence of recurrence for more than 6 years after surgery.
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spelling pubmed-50432532016-10-07 Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas Saito, Hiroyuki Kashiyama, Hiroshi Murohashi, Takashi Sasaki, Kazunari Misawa, Ryosuke Ohwada, Susumu Case Rep Gastroenterol Case and Review Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasion. The patient underwent radical distal pancreatectomy and was subsequently treated with adjuvant chemotherapy using gemcitabine plus S-1 followed by maintenance chemotherapy with oral tegafur-uracil. The patient has been doing well with no evidence of recurrence for more than 6 years after surgery. S. Karger AG 2016-08-31 /pmc/articles/PMC5043253/ /pubmed/27721735 http://dx.doi.org/10.1159/000448878 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case and Review
Saito, Hiroyuki
Kashiyama, Hiroshi
Murohashi, Takashi
Sasaki, Kazunari
Misawa, Ryosuke
Ohwada, Susumu
Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title_full Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title_fullStr Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title_full_unstemmed Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title_short Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas
title_sort case of six-year disease-free survival with undifferentiated carcinoma of the pancreas
topic Case and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043253/
https://www.ncbi.nlm.nih.gov/pubmed/27721735
http://dx.doi.org/10.1159/000448878
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