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Importance of metabolic rate to the relationship between the number of genes in a functional category and body size in Peto's paradox for cancer
Elucidation of tumour suppression mechanisms is a major challenge in cancer biology. Therefore, Peto's paradox, or low cancer incidence in large animals, has attracted focus. According to the gene-abundance hypothesis, which considers the increase/decrease in cancer-related genes with body size...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043308/ https://www.ncbi.nlm.nih.gov/pubmed/27703689 http://dx.doi.org/10.1098/rsos.160267 |