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Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043365/ https://www.ncbi.nlm.nih.gov/pubmed/27721785 http://dx.doi.org/10.1159/000447737 |
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author | Chaidaroon, Winai Supalaset, Sumet Tananuvat, Napaporn Vanittanakom, Nongnuch |
author_facet | Chaidaroon, Winai Supalaset, Sumet Tananuvat, Napaporn Vanittanakom, Nongnuch |
author_sort | Chaidaroon, Winai |
collection | PubMed |
description | PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea. Numerous septate hyphal fragments were detected in a corneal specimen, and nucleotide sequence analysis identified B. hawaiiensis. Treatment was started with 5% natamycin eyedrops and oral itraconazole. Subsequently, a corneal plaque developed which did not respond to medication and debridement. The patient underwent therapeutic penetrating keratoplasty. CONCLUSIONS: B. hawaiiensis is a rare cause of corneal phaeohyphomycosis. A brownish pigmented infiltration is an important diagnostic clue, however microbiologic studies are required to obtain a definite diagnosis. Although antifungal medication and debridement are the mainstay of most corneal fungal infection, therapeutic penetrating keratoplasty can prevent morbidity related to this fungal infection. |
format | Online Article Text |
id | pubmed-5043365 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-50433652016-10-07 Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis Chaidaroon, Winai Supalaset, Sumet Tananuvat, Napaporn Vanittanakom, Nongnuch Case Rep Ophthalmol Case Report PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea. Numerous septate hyphal fragments were detected in a corneal specimen, and nucleotide sequence analysis identified B. hawaiiensis. Treatment was started with 5% natamycin eyedrops and oral itraconazole. Subsequently, a corneal plaque developed which did not respond to medication and debridement. The patient underwent therapeutic penetrating keratoplasty. CONCLUSIONS: B. hawaiiensis is a rare cause of corneal phaeohyphomycosis. A brownish pigmented infiltration is an important diagnostic clue, however microbiologic studies are required to obtain a definite diagnosis. Although antifungal medication and debridement are the mainstay of most corneal fungal infection, therapeutic penetrating keratoplasty can prevent morbidity related to this fungal infection. S. Karger AG 2016-07-21 /pmc/articles/PMC5043365/ /pubmed/27721785 http://dx.doi.org/10.1159/000447737 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Chaidaroon, Winai Supalaset, Sumet Tananuvat, Napaporn Vanittanakom, Nongnuch Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title | Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title_full | Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title_fullStr | Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title_full_unstemmed | Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title_short | Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis |
title_sort | corneal phaeohyphomycosis caused by bipolaris hawaiiensis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043365/ https://www.ncbi.nlm.nih.gov/pubmed/27721785 http://dx.doi.org/10.1159/000447737 |
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