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Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis

PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A...

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Autores principales: Chaidaroon, Winai, Supalaset, Sumet, Tananuvat, Napaporn, Vanittanakom, Nongnuch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043365/
https://www.ncbi.nlm.nih.gov/pubmed/27721785
http://dx.doi.org/10.1159/000447737
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author Chaidaroon, Winai
Supalaset, Sumet
Tananuvat, Napaporn
Vanittanakom, Nongnuch
author_facet Chaidaroon, Winai
Supalaset, Sumet
Tananuvat, Napaporn
Vanittanakom, Nongnuch
author_sort Chaidaroon, Winai
collection PubMed
description PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea. Numerous septate hyphal fragments were detected in a corneal specimen, and nucleotide sequence analysis identified B. hawaiiensis. Treatment was started with 5% natamycin eyedrops and oral itraconazole. Subsequently, a corneal plaque developed which did not respond to medication and debridement. The patient underwent therapeutic penetrating keratoplasty. CONCLUSIONS: B. hawaiiensis is a rare cause of corneal phaeohyphomycosis. A brownish pigmented infiltration is an important diagnostic clue, however microbiologic studies are required to obtain a definite diagnosis. Although antifungal medication and debridement are the mainstay of most corneal fungal infection, therapeutic penetrating keratoplasty can prevent morbidity related to this fungal infection.
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spelling pubmed-50433652016-10-07 Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis Chaidaroon, Winai Supalaset, Sumet Tananuvat, Napaporn Vanittanakom, Nongnuch Case Rep Ophthalmol Case Report PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea. Numerous septate hyphal fragments were detected in a corneal specimen, and nucleotide sequence analysis identified B. hawaiiensis. Treatment was started with 5% natamycin eyedrops and oral itraconazole. Subsequently, a corneal plaque developed which did not respond to medication and debridement. The patient underwent therapeutic penetrating keratoplasty. CONCLUSIONS: B. hawaiiensis is a rare cause of corneal phaeohyphomycosis. A brownish pigmented infiltration is an important diagnostic clue, however microbiologic studies are required to obtain a definite diagnosis. Although antifungal medication and debridement are the mainstay of most corneal fungal infection, therapeutic penetrating keratoplasty can prevent morbidity related to this fungal infection. S. Karger AG 2016-07-21 /pmc/articles/PMC5043365/ /pubmed/27721785 http://dx.doi.org/10.1159/000447737 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Chaidaroon, Winai
Supalaset, Sumet
Tananuvat, Napaporn
Vanittanakom, Nongnuch
Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title_full Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title_fullStr Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title_full_unstemmed Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title_short Corneal Phaeohyphomycosis Caused by Bipolaris hawaiiensis
title_sort corneal phaeohyphomycosis caused by bipolaris hawaiiensis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043365/
https://www.ncbi.nlm.nih.gov/pubmed/27721785
http://dx.doi.org/10.1159/000447737
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