Granular cell tumour developing in the background of a previous mandibular giant cell lesion: Case report

INTRODUCTION: Granular cell tumours of the mandible are very rare. We present a unique case which has developed at the site of a previous giant cell lesion. PRESENTATION: 51 year old Caucasian lady had excision of a recurrent giant cell lesion of the anterior mandible. Follow up showed evidence of radiographic recurrence. However, further biopsies from the same site showed granular cell tumour with soft tissues extension. The patient remains well on long term follow up with no evidence of recurrence. DISCUSSION: This case is unique because the granular cell tumour has evolved from the site of a recurrent giant cell lesion. Conservative surgical excision was an adequate treatment option. CONCLUSION: Within the limitations of our case study, a correlation between granular cell tumour and giant cell lesion is possible. However, more research is needed to prove this.